Research Unit: Instituto de Neurociencias

Web page: 

http://www.umh.es/contenido/Estudiantes/:persona_4287/datos_es.html

http://in.umh.es/grupos-detalle.aspx?grupo=15

Research Fields: Molecular Biology, and Pharmacology of Acetylcholine Nicotinic Receptors

Representative Publications:

Criado, M., Balsera, B., Mulet, J., Sala, S., Sala, F., de la Torre-Martínez, R., Fernández-Carvajal, A., Ferrer-Montiel, A., Moreno-Fernández, S., Miguel, M., Pérez de Vega, M.J., González-Muñiz, R. (2016) 1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties. Future Med. Chem. 8, 731-749.

Criado, M., Mulet, J., Sala, F., Sala, S., Colmena I, Gandía, L., Bautista-Aguilera, O.M., Samadi, A., Chioua, M., Marco-Contelles, J. (2016) N-benzylpiperidine derivatives as a7 nicotinic receptor antagonists. ACS Chem. Neurosci. 7, 1157-1165.

Criado, M. (2018) Acetylcholine nicotinic receptor subtypes in chromaffin cells. Pflugers Arch. Eur. J. Physiol. 470, 13-20.

Balsera, B., Mulet, J., Sala, S., Sala, F., de la Torre-Martínez, R., González-Rodríguez, S., Plata, A., Naesens, L., Fernández-Carvajal, A., Ferrer-Montiel, A., Criado, M., Pérez de Vega, M.J., González-Muñiz, R. (2018) Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of a7 nicotinic receptors with analgesic activity. Eur. J. Med. Chem. 143, 157-165.

Torrealba, D., Balasch, J.C., Criado, M., Tort, L., Mackenzie, S., Roher, N. (2018) Functional evidence for the inflammatory reflex in teleosts: A novel a7 nicotinic acetylcholine receptor modulates the macrophage response to dsRNA. Dev. Comp. Immunol. 84, 279-291.

Patents:

Criado, M., Mulet, J., Sala, S., Sala, F., Fernández-Carvajal, A., González-Muñiz, R., Pérez de Vega, M.J., Balsera, B., Borges, R. Referencia ES2047.13. Moduladores del receptor nicotínico de acetilcolina alfa7 y sus usos. España 02 octubre 2013.

Available Technologies:

Nucleic Acids: purification, characterization and modification

Proteins: expression in bacterial and eukaryotic systems.

Cultures: bacterial and eukaryotic cultures. Transfections.